Certificate of Analysis

 

Product Name: SZUH280 
Catalog Number: M29824
CAS Number: 2770263-77-7

Physical and Chemical Properties
Formula: C36H34N8O8
Molecular Weight: 706.7
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: SZUH280  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: SZUH280 is a potent and selective PROTAC HDAC8 degrader with a DC50 of 0.58 μM in A549 cells. SZUH280 induces cancer cell apoptosis. SZUH280 hampers DNA damage repair in cancer cells, promoting cellular radiosensitization.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.