Certificate of Analysis

 

Product Name: STL1267
Catalog Number: M45382
CAS Number: 1429024-58-7

Physical and Chemical Properties
Formula: C17H11ClN4O
Molecular Weight: 322.75
Form: Solid
Solubility: DMSO 25 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: STL1267 Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: STL1267 is a potent REV-ERB agonist that crosses the blood-brain barrier with a Ki value of 0.16 µM for REV-ERBα. STL1267 showed no cytotoxicity and inhibited BMAL1 gene expression.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.