Certificate of Analysis
| Product Name: | SRT1720 Hydrochloride |
| Catalog Number: | M1824 |
| CAS Number: | 1001645-58-4 |
Physical and Chemical Properties
| Formula: | C25H23N7OS.HCl |
| Molecular Weight: | 506.02 |
| Solubility: | DMSO ≥ 30 mg/mL; Water 5 mg/mL |
| Storage: | -20°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 100.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SRT1720 Hydrochloride is a selective small molecule activator of SIRT1 that is 1,000-fold more potent than resveratrol (EC1.5 = 0.16 versus 46.2 µM, respectively). SRT1720 increased the activity of SIRT1 and AMPKα phosphorylation at Ser485 via the cAMP-protein kinase A (PKA) pathway. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |