Certificate of Analysis

 

Product Name: SR 3677
Catalog Number: M5339
CAS Number: 1072959-67-1

Physical and Chemical Properties
Formula: C22H24N4O4
Molecular Weight: 408.45
Solubility: 10mM in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: SR 3677 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: SR-3677 is a new potent and selective ROCK-II inhibitor with an IC50 of ~3 nM in enzyme and cell based assays; IC50 for ROCK-I is 56 ± 12 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.