Certificate of Analysis

 

Product Name: SJ10542
Catalog Number: M49776
CAS Number: 2789678-92-6

Physical and Chemical Properties
Formula: C41H46N12O5S
Molecular Weight: 818.95
Form: Solid
Solubility: DMSO 40 mg/mL (ultrasonic)
Storage: 4°C, dry, sealed
Chemical Structure: SJ10542 Structure
Analytical Data
QC Standard: ≥99.5%
H-NMR: Consistent with structure
Product Information
Description: SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC50s of 14, 11, and 24 nM for JAK2, JAK3, and JAK2-fusion ALL, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.