Certificate of Analysis

 

Product Name: SEW2871
Catalog Number: M2476
CAS Number: 256414-75-2

Physical and Chemical Properties
Formula: C20H10F6N2OS
Molecular Weight: 440.36
Form: Solid
Solubility: DMSO 10 mg/mL
Storage: Powder -20°C
Chemical Structure: SEW2871 Structure
Analytical Data
QC Standard: 99.74%
H-NMR: Consistent with structure
Product Information
Description: SEW2871 is an orally active, potent, highly selective S1P1 (sphingosine-1-phosphate type 1 receptor) agonist, with an EC50 of 13.8 nM. SEW2871 activates ERK, Akt, and Rac signaling pathways and induces S1P1 internalization and recycling.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.