Certificate of Analysis
| Product Name: | Setidegrasib |
| Catalog Number: | M58644 |
| CAS Number: | 2821793-99-9 |
Physical and Chemical Properties
| Formula: | C60H65FN12O7S |
| Molecular Weight: | 1117.3 |
| Form: | Solid |
| Solubility: | DMSO 90 mg/mL |
| Storage: | -20°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Setidegrasib is a PROTAC KRAS degrader (DC50: 37 nM). Setidegrasib induces the degradation of G12D-mutation KRAS protein. Setidegrasib has antitumor effect. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |