Certificate of Analysis

 

Product Name: SAR407899
Catalog Number: M9678
CAS Number: 923359-38-0

Physical and Chemical Properties
Formula: C14H16N2O2
Molecular Weight: 244.29
Solubility: DMSO ≥ 5 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: SAR407899 Structure
Analytical Data
QC Standard: 100.0%
H-NMR: Consistent with structure
Product Information
Description: SAR407899 is a potent and selective, ATP-competitive ROCK inhibitor with IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.