Certificate of Analysis
| Product Name: | SAH-SOS1A TFA |
| Catalog Number: | M10600 |
| CAS Number: | 1652561-87-9 (free base) |
Physical and Chemical Properties
| Formula: | C102H160N27F3O30 |
| Molecular Weight: | 2301.55 |
| Storage: | -20°C, protect from light, sealed |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC50=106-175 nM) and directly and independently blocks nucleotide association. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |