Certificate of Analysis
| Product Name: | RSM-932A |
| Catalog Number: | M30694 |
| CAS Number: | 850807-63-5 |
Physical and Chemical Properties
| Formula: | C46H38Br2Cl2N4 |
| Molecular Weight: | 877.53 |
| Form: | Solid |
| Solubility: | DMSO 16.67 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | 4°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | RSM-932A (TCD-717) is a specific ChoKα inhibitor with IC50s of 1 and 33 μM for human recombinant ChoKα and ChoKβ enzymes, respectively. RSM-932A acts as the “first in humans” compound targeting ChoKα. RSM-932A is potent in vitro anti-proliferative and in vivo anti-tumoral activity against human xenografts in mice, showing high efficacy with low toxicity profiles. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |