Certificate of Analysis


Catalog Number: M5939
Product Name: Rolipram
CAS Number: 61413-54-5

Physical and Chemical Properties
Formula: C16H21NO3
Molecular Weight: 275.34
Solubility: DMSO 30 mg/mL
Storage: at -20°C
Chemical Structure: Rolipram Structure
Analytical Data
HPLC: Shows Min 99.1% purity
H-NMR: Consistent with structure
Product Information
Description: The PDE4 selective inhibitor, rolipram, inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.