| Description: |
RNA Synthesis IN-1 (a substitute for Actinomycin D) is an inhibitor of RNA and protein synthesis, with antibacterial and anti-tumor effects. RNA Synthesis IN-1 can inhibit the protein synthesis of bacteria, directly bind to the guanine groups of single-stranded or double-stranded DNA in the transcriptional initiation complex, inhibit the activity of DNA-dependent RNA polymerase, and interfere with the transcription process of DNA, thereby inhibiting mRNA synthesis. RNA Synthesis IN-1 inhibits DNA repair with an IC50 value of 0.42 μM. |
| Stability and Solubility Advice: |
Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |
