Certificate of Analysis

 

Product Name: RM-018
Catalog Number: M11427
CAS Number: 2641993-55-5

Physical and Chemical Properties
Formula: C56H72N8O8
Molecular Weight: 985.22
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: RM-018  Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: RM-018 is an inhibitor of the active state of KRASG12C. Rm-018 retains the ability to bind and inhibit KRASG12C/Y96D. Rm-018 combines with GTP-bound to activate the [" RAS(ON) "] state of KRASG12C.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.