Certificate of Analysis
| Product Name: | RIG012 |
| Catalog Number: | M40694 |
| CAS Number: | 2642218-43-5 |
Physical and Chemical Properties
| Formula: | C23H21NO3 |
| Molecular Weight: | 359.42 |
| Form: | Solid |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | RIG012 is a potent RIG-I antagonist that blocks RIG-I-initiated signaling, inhibits transcriptional induction of CXCL10, IFN-β 1, and IRF9, and reduces IL6 mRNA levels. The IC50 was 0.71 μM when assayed with NADH-coupled ATPase. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |