Certificate of Analysis
| Product Name: | Rho-Kinase-IN-2 |
| Catalog Number: | M49537 |
| CAS Number: | 2573071-18-6 |
Physical and Chemical Properties
| Formula: | C20H25FN4O2 |
| Molecular Weight: | 372.44 |
| Form: | Solid |
| Solubility: | DMSO 50 mg/mL (ultrasonic) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Rho-Kinase-IN-2 is an orally active, selective, and central nervous system (CNS)-penetrant Rho Kinase (ROCK) inhibitor (ROCK2 IC50=3 nM). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |