| Product Name: | Recombinant Mouse Siglec-15 Protein (HEK293, C-6His) |
| Catalog Number: | M66397 |
| Form: | Lyophilized powder |
| Solubility: | Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL. |
| Storage: | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| Description: | Siglec-15 is constitutively expressed in osteoclasts, macrophages and dendritic cells. Siglec-15 function is important for osteoclast formation and TRANCE/RANK Ligand signaling in osteoclasts. Siglec-15 plays a pivotal role in the development and differentiation of osteoclastogenesis, inhibiting antigen-specific T cell responses in vitro and in vivo. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |