Certificate of Analysis
| Product Name: | Ranolazine dihydrochloride |
| Catalog Number: | M3956 |
| CAS Number: | 95635-56-6 |
Physical and Chemical Properties
| Formula: | C24H35Cl2N3O4 |
| Molecular Weight: | 500.46 |
| Form: | Solid |
| Solubility: | DMSO 100mg/ml; water 100mg/ml |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Ranolazine (CVT 303) is an anti-angina and anti-ischemia agent that works by inhibiting the late effects of inward sodium current (IC50 values of 6 μM and 12 μM for INa and IKr, respectively) without affecting heart rate or blood pressure. Ranolazine is also a partial inhibitor of fatty acid oxidation (FAO). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |