Certificate of Analysis
| Product Name: | R406 besylate |
| Catalog Number: | M14916 |
| CAS Number: | 841290-81-1 |
Physical and Chemical Properties
| Formula: | C22H23FN6O5.C6H6O3S |
| Molecular Weight: | 628.63 |
| Solubility: | DMSO ≥ 61 mg/mL |
| Storage: | 2-8°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98.5% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | R406 is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |