Certificate of Analysis

 

Product Name: R-7050
Catalog Number: M8516
CAS Number: 303997-35-5

Physical and Chemical Properties
Formula: C16H8ClF3N4S
Molecular Weight: 380.77
Solubility: DMSO 20 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: R-7050 Structure
Analytical Data
QC Standard: 98.48%
H-NMR: Consistent with structure
Product Information
Description: R-7050 is a cell-permeable TNF-α receptor antagonist that blocks TNF-α-induced binding of TNF-αRI with TNFαR-associated death domain protein and receptor interacting protein 1, blocking internalization of the TNFα-TNFαR complex.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.