Certificate of Analysis
| Product Name: | QS-21 |
| Catalog Number: | M10611 |
| CAS Number: | 141256-04-4 |
Physical and Chemical Properties
| Formula: | C92H148O46 |
| Molecular Weight: | 1990.13 |
| Solubility: | DMSO 80 mg/mL; Water 40 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.87% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant. QS-21 stimulates Th2 humoral and Th1 cell-mediated immune responses through action on antigen presenting cells (APCs) and T cells. QS-21 can activate the NLRP3 inflammasome with subsequent release of caspase-1 dependent cytokines, IL-1β and IL-18. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |