Certificate of Analysis


Product Name: Pulrodemstat benzenesulfonate
Catalog Number: M10727
CAS Number: 2097523-60-7

Physical and Chemical Properties
Formula: C30H29F2N5O5S
Molecular Weight: 609.65
Solubility: DMSO ≥ 60 mg/mL
Storage: -20°C, dry, sealed
Chemical Structure: Pulrodemstat benzenesulfonate Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: CC-90011 (Pulrodemstat) benzenesulfonate is a potent, selective, reversible and orally active lysine-specific demethylase-1 (LSD1) inhibitor,IC50 0.25 nM. CC-90011 benzenesulfonate has less enzymatic inhibition of LSD2, MOA-A and MAO-B. CC-90011 benzenesulfonate induces differentiation of acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells and has potent anti-cancer activity.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.