Certificate of Analysis
| Product Name: | PKM2-IN-1 |
| Catalog Number: | M6261 |
| CAS Number: | 94164-88-2 |
Physical and Chemical Properties
| Formula: | C18H19NO2S2 |
| Molecular Weight: | 345.48 |
| Form: | Solid |
| Solubility: | DMSO 7 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PKM2-IN-1 (compound 3k) is a pyruvate kinase M2 (PKM2) inhibitor with an IC50 of 2.95 μM. The IC50 value for PKM1 is 4-5-fold higher than that for PKM2. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |