Certificate of Analysis


Product Name: Phorbol 12-myristate 13-acetate
Catalog Number: M4647
CAS Number: 16561-29-8

Physical and Chemical Properties
Formula: C36H56O8
Molecular Weight: 616.83
Solubility: DMSO 90 mg/mL, Ethanol 90 mg/mL
Storage: -20°C, protect from light
Chemical Structure: Phorbol 12-myristate 13-acetate Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: Phorbol 12-myristate 13-acetate (PMA) is a dual SphK and protein kinase C (PKC) activator, increases the intracellular Ca2+ concentration ([Ca2+]i) in a dose-dependent manner, with an EC50 of 11.7 nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.