Certificate of Analysis
| Product Name: | Phorbol 12-myristate 13-acetate |
| Catalog Number: | M4647 |
| CAS Number: | 16561-29-8 |
Physical and Chemical Properties
| Formula: | C36H56O8 |
| Molecular Weight: | 616.83 |
| Solubility: | DMSO 90 mg/mL; Ethanol 90 mg/mL |
| Storage: | -20°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Phorbol 12-myristate 13-acetate (PMA) is a dual SphK and protein kinase C (PKC) activator, increases the intracellular Ca2+ concentration ([Ca2+]i) in a dose-dependent manner, with an EC50 of 11.7 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |