Certificate of Analysis
| Product Name: | PF-06751979 |
| Catalog Number: | M13414 |
| CAS Number: | 1818339-66-0 |
Physical and Chemical Properties
| Formula: | C18H19F2N5O3S2 |
| Molecular Weight: | 455.5 |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PF-06751979 is a potent, brain permeable inhibitor of β -amyloid precursor protein lyase 1 (BACE1) with an IC50 of 7.3 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |