Certificate of Analysis

 

Product Name: Palosuran hydrochloride
Catalog Number: M14066
CAS Number: 2469274-58-4

Physical and Chemical Properties
Molecular Weight: 454.99
Solubility: DMSO 50 mg/mL; Water 7.14 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: Palosuran hydrochloride Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Palosuran hydrochloride (ACT-058362 hydrochloride) is a potent, selective, and orally active antagonist of urotensin II receptor, with an IC50 of 3.6 nM for CHO cell membranes expressing human recombinant receptors.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.