Certificate of Analysis

 

Product Name: Oclacitinib maleate
Catalog Number: M5827
CAS Number: 1640292-55-2

Physical and Chemical Properties
Formula: C15H23N5O2S.C4H4O4
Molecular Weight: 453.51
Solubility: 70 mg/mL in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Oclacitinib maleate Structure
Analytical Data
QC Standard: 99.23%
H-NMR: Consistent with structure
Product Information
Description: Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.