Certificate of Analysis
| Product Name: | Numidargistat dihydrochloride |
| Catalog Number: | M14069 |
| CAS Number: | 2095732-06-0 (free base) |
Physical and Chemical Properties
| Molecular Weight: | 360.04 |
| Solubility: | DMSO 55 mg/mL; Water 37.78 mg/mL |
| Storage: | -20°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Numidargistat (CB-1158) dihydrochloride is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |