Certificate of Analysis
| Product Name: | NSC23766 trihydrochloride |
| Catalog Number: | M2889 |
| CAS Number: | 1177865-17-6 |
Physical and Chemical Properties
| Formula: | C24H35N7.3HCl |
| Molecular Weight: | 530.96 |
| Solubility: | Water: ≥ 25 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.76% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NSC23766 3HCl is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM; does not inhibit the closely related targets, Cdc42 or RhoA. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |