Certificate of Analysis

 

Product Name: NRD-21
Catalog Number: M49480

Physical and Chemical Properties
Solubility: DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: NRD-21 Structure
Analytical Data
QC Standard: >98.0%
Product Information
Description: NRD-21 is an allosteric inhibitor of PAR1 Gq signaling, with IC50 of 0.38 uM in intracellular calcium mobilization assay. NRD-21 has improved anti-Inflammatory activity and is much more plasma stable than ML161, it is a promising lead compound for the parmodulin class for anti-thrombotic and anti-inflammatory indications research.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.