Certificate of Analysis
| Product Name: | NNK |
| Catalog Number: | M30412 |
| CAS Number: | 64091-91-4 |
Physical and Chemical Properties
| Formula: | C10H13N3O2 |
| Molecular Weight: | 207.23 |
| Form: | Solid |
| Solubility: | DMSO ≥ 62.5 mg/mL |
| Storage: | Powder -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.83% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NNK is a nicotine-nitrosated derivative. NNK simultaneously stimulates Bcl2 phosphorylation exclusively at Ser70 and c-Myc at Thr58 and Ser62 through activation of both ERK1/2 and PKCα. NNK induces survival and proliferation of human lung cancer cells. NNK can be used for lung cancer mice model structure. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |