Certificate of Analysis
| Product Name: | NCOA4-9a |
| Catalog Number: | M58970 |
| CAS Number: | 2650557-72-3 |
Physical and Chemical Properties
| Formula: | C27H28FN5 |
| Molecular Weight: | 441.54 |
| Solubility: | DMSO 30 mg/mL |
| Storage: | -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NCOA4-9a (NCOA4-FTH1 inhibitor 9a) is a new ferroptosis inhibitor through disrupting the NCOA4-FTH1 protein-protein interaction, reduces intracellular ferrous iron, inhibits Erastin-induced ferroptosiswith EC50 of 0.29 μM in HT22 cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |