Certificate of Analysis

 

Product Name: NBD-14270 
Catalog Number: M29610
CAS Number: 2411819-82-2

Physical and Chemical Properties
Formula: C18H18F3N5O2S
Molecular Weight: 425.43
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: 4°C, protect from light, dry, sealed
Chemical Structure: NBD-14270  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC50>100 μM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.