Certificate of Analysis

 

Catalog Number: M14139
Product Name: Naquotinib mesylate
CAS Number: 1448237-05-5

Physical and Chemical Properties
Formula:
Molecular Weight: 658.81
Solubility: DMSO 12.5 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: Naquotinib mesylate Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Naquotinib mesylate (ASP8273 mesylate) is an orally available, mutant-selective and irreversible EGFR inhibitor; with IC50s of 8-33 nM toward EGFR mutants and 230 nM for EGFR.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.