Certificate of Analysis

 

Product Name: NAPQI 
Catalog Number: M30204
CAS Number: 50700-49-7

Physical and Chemical Properties
Formula: C8H7NO2
Molecular Weight: 149.15
Form: Solid
Storage: -80°C, protect from light, sealed
Chemical Structure: NAPQI  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: NAPQI is the toxic metabolite of Acetaminophen. NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.