Certificate of Analysis
| Product Name: | MRTX849 acid |
| Catalog Number: | M21503 |
| CAS Number: | 2561529-96-0 |
Physical and Chemical Properties
| Formula: | C34H37ClFN7O4 |
| Molecular Weight: | 662.15 |
| Solubility: | N/A |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| HPLC: | Shows Min ＞98% purity |
| H-NMR: | Consistent with structure |
Product Information
| Description: | MRTX849 acid can be used to synthesize PROTAC LC-2. LC-2 is a potent, first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50, between 0.25 and 0.76 μM). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |