Certificate of Analysis

 

Product Name: MRTX849 acid
Catalog Number: M21503
CAS Number: 2561529-96-0

Physical and Chemical Properties
Formula: C34H37ClFN7O4
Molecular Weight: 662.15
Solubility: N/A
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: MRTX849 acid  Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: MRTX849 acid can be used to synthesize PROTAC LC-2. LC-2 is a potent, first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50, between 0.25 and 0.76 μM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.