Certificate of Analysis
| Product Name: | MPTP HCl |
| Catalog Number: | M9049 |
| CAS Number: | 23007-85-4 |
Physical and Chemical Properties
| Formula: | C12H16ClN |
| Molecular Weight: | 209.72 |
| Solubility: | Water ≥ 55 mg/mL; DMSO ≥ 5 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.89% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |