Certificate of Analysis
| Product Name: | ML385 |
| Catalog Number: | M8692 |
| CAS Number: | 846557-71-9 |
Physical and Chemical Properties
| Formula: | C29H25N3O4S |
| Molecular Weight: | 511.59 |
| Solubility: | DMSO ≥ 25 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 100.00% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | ML385 was a specific nuclear factor erythroid 2-related factor 2 (NRF2) inhibitor with an IC50 of 1.9 μM. ML385 inhibits Nrf2 transcription factor activity by binding to Neh1. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |