Certificate of Analysis

 

Product Name: ML381
Catalog Number: M28713
CAS Number: 1623481-80-0

Physical and Chemical Properties
Formula: C21H21N3O4
Molecular Weight: 379.41
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: ML381 Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: ML381 (VU0488130) is a highly selective, central nervous system penetrant mAChR M5 orthogonal antagonist (IC50 = 450 nM; Ki = 340 nM). ML381 is unstable in rat plasma and can be mainly used as a molecular probe for in vitro and electrophysiological studies.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.