Certificate of Analysis
| Product Name: | MK-8153 |
| Catalog Number: | M21142 |
| CAS Number: | 1548286-45-8 |
Physical and Chemical Properties
| Formula: | C24H28N2O6 |
| Molecular Weight: | 440.49 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | MK-8153 is a potent, selective and orally active extrarenal medullary potassium channel (ROMK) inhibitor with IC50 values of 5 nM and 34 μM for ROMK EP and hERG EP, respectively.MK-8153 can be used as a diuretic. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |