Certificate of Analysis
| Product Name: | Mitoxantrone dihydrochloride |
| Catalog Number: | M2217 |
| CAS Number: | 70476-82-3 |
Physical and Chemical Properties
| Formula: | C22H28N4O6.2HCl |
| Molecular Weight: | 517.4 |
| Solubility: | DMSO 30 mg/mL; Water 60 mg/mL |
| Storage: | 2-8°C, protect from light, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.71% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |