Certificate of Analysis

 

Product Name: Lusutrombopag
Catalog Number: M9458
CAS Number: 1110766-97-6

Physical and Chemical Properties
Formula: C29H32Cl2N2O5S
Molecular Weight: 591.55
Solubility: DMSO 30 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Lusutrombopag Structure
Analytical Data
QC Standard: >98.0%
H-NMR: Consistent with structure
Product Information
Description: Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist. Lusutrombopag acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.