Certificate of Analysis
| Product Name: | LEO 134310 |
| Catalog Number: | M21063 |
| CAS Number: | 2089130-74-3 |
Physical and Chemical Properties
| Formula: | C34H40N2O8 |
| Molecular Weight: | 604.69 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | LEO 134310 is a non-steroidal, selective glucocorticoid receptor (GR) agonist that is being studied in the first phase of plaque psoriasis.LEO 134310 has shown high affinity (EC50 of 14 nM) in GR binding assays.LEO 134310 can be used in dermatological conditions. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |