Certificate of Analysis
| Product Name: | LCZ696 |
| Catalog Number: | M5731 |
| CAS Number: | 936623-90-4 |
Physical and Chemical Properties
| Formula: | C24H29N5O3.C24H29NO5.5/2H2O.3Na |
| Molecular Weight: | 915.98 |
| Solubility: | Water 50 mg/mL; DMSO 50 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.5% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | LCZ696, consisting of Valsartan and Sacubitril in a 1:1 molar ratio, is a first-in-class dual-action angiotensin receptor-neprilysin inhibitor (ARNi,angiotensin receptor-neprilysin inhibitor) for the study of hypertension and heart failure. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |