Certificate of Analysis


Catalog Number: M1802
Product Name: Lapatinib Ditosylate
CAS Number: 388082-78-8

Physical and Chemical Properties
Formula: C29H26ClFN4O4S.2C7H8O3S
Molecular Weight: 925.46
Solubility: DMSO 90 mg/mL
Storage: -20°C, sealed, protect from light
Chemical Structure: Lapatinib Ditosylate Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Lapatinib Ditosylate (CAS 388082-78-8) is a selective and effective inhibitor of EGFR kinase (Ki = 3 nM), ErbB-2 kinase (Ki = 13 nM) and ErbB-4 kinase (Ki = 347 nM).
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.