Certificate of Analysis
| Product Name: | L-Buthionine-sulfoximine |
| Catalog Number: | M3865 |
| CAS Number: | 83730-53-4 |
Physical and Chemical Properties
| Formula: | C8H18N2O3S |
| Molecular Weight: | 222.31 |
| Solubility: | Water: ≥ 30 mg/mL (Need ultrasonic; pH 7.2) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.76% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | L-buthionine-sulfoximine is a cell-permeable, potent, fast-acting, irreversible g-glutamylcysteine synthetase inhibitor that consumes endogenous endogenous intracellular copper chelating agent glutathione. Sensitized cells to cell death induced by Elesclomol-copper, and the efficacy of statin inhibitors was enhanced by combination. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |