Certificate of Analysis
| Product Name: | KZR-504 |
| Catalog Number: | M28727 |
| CAS Number: | 1629052-78-3 |
Physical and Chemical Properties
| Formula: | C21H23N3O6 |
| Molecular Weight: | 413.42 |
| Form: | Solid |
| Solubility: | DMSO 170 mg/mL (ultrasonic) |
| Storage: | -20°C, protect from light, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | KZR-504 is a highly selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2), with IC50s of 51 nM, 4.274 μM for LMP2 and LMP7, respectively. KZR-504 is of interest for the treatment of autoimmune disease. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |