Certificate of Analysis


Catalog Number: M3719
Product Name: K145 hydrochloride
CAS Number: 1449240-68-9

Physical and Chemical Properties
Formula: C18H24N2O3S.HCl
Molecular Weight: 384.92
Solubility: Water 90 mg/mL, DMSO 40 mg/mL
Storage: at -20°C
Chemical Structure: K145 hydrochloride Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: K145 hydrochloride is a selective SphK2 inhibitor with an IC50 of 4.30±0.06 μM , while no inhibition of SphK1 at concentrations up to 10 μM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.