Certificate of Analysis
| Product Name: | JPE-1375 |
| Catalog Number: | M58630 |
| CAS Number: | 1254036-23-1 |
Physical and Chemical Properties
| Formula: | C49H63FN10O9 |
| Molecular Weight: | 955.08 |
| Form: | Solid |
| Solubility: | DMSO 96 mg/mL |
| Storage: | 4°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | JPE-1375 is a complement C5a receptor 1 (C5aR1) antagonist. JPE-1375 effectively inhibits polymorphonuclear leukocyte mobilization (EC50=6.9 µM) and reduces TNF levels (EC50=4.5 µM) in mice. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |