Certificate of Analysis

 

Product Name: JNJ-1013
Catalog Number: M41291
CAS Number: 2597343-08-1

Physical and Chemical Properties
Formula: C46H55N9O7S
Molecular Weight: 878.05
Form: Solid
Solubility: DMSO 20 mg/mL (ultrasonic and warming)
Storage: 4°C, protect from light
Chemical Structure: JNJ-1013 Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: JNJ-1013 is a potent and selective IRAK1 degrader with an IC50s of 72, 443, 1071 nM for IRAK1, IRAK4, VHL FP respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.