Certificate of Analysis

 

Product Name: JANEX-1
Catalog Number: M5028
CAS Number: 202475-60-3

Physical and Chemical Properties
Formula: C16H15N3O3
Molecular Weight: 297.31
Solubility: DMSO:~1 mg/ml
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: JANEX-1 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (IC50 = 78 μM); has no effect on JAK1, JAK2, or Zap/Syk or SRC tyrosine kinases.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.